Fused silica-packed capillary columns containing vancomycin immobilized by reductive amination on an aldehyde-silica were used to separate enantiomers of some non-steroidal anti-inflammatory drugs. Attempts have been made to qualitatively explain the influence of various mobile phase compositions on
✦ LIBER ✦
Polar organic phase liquid chromatography with packed capillary columns using a vancomycin chiral stationary phase
✍ Scribed by Lars A. Svensson; Jürgen Dönnecke; Karl-Erik Karlsson; Anders Karlsson; Jörgen Vessman
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 262 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0899-0042
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Vancomycin immobilized on an aldehyde functionalized silica support in packed capillary columns has been used as a chiral stationary phase in supercritical fluid chromatography under subcritical conditions. The use of carbon dioxide with methanol as the mobile phase modifier is shown to offer an ext