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Point mutations in the pre-core region of HBV in anti-HBe positive patients with chronic hepatitis and persistent HBV replication

✍ Scribed by Carman, W; Jeeyna, M; Karayiannis, P; Hadziyannis, S; Thomas, HC


Book ID
123053621
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
47 KB
Volume
9
Category
Article
ISSN
0168-8278

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## Abstract Some chronic HBV carriers have circulating HBV DNA despite the presence of anti‐HBeAg antibodies. This observation has recently been related to the presence, in the HBV pre‐C region, of a translational stop codon that prevents HBeAg synthesis. In the present study, we analyzed, at the n