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Point mutations associated with insecticide resistance in the Drosophila cytochrome P450 Cyp6a2 enable DDT metabolism

✍ Scribed by Marcel Amichot; Sophie Tarès; Alexandra Brun-Barale; Laury Arthaud; Jean-Marc Bride; Jean-Baptiste Bergé


Book ID
110914961
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
310 KB
Volume
271
Category
Article
ISSN
1432-1327

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A novel mutation that generates a stop codon in the third exon of the gene encoding the cytochrome P-450 CYP2D6 was identified in a Caucasian having a deficiency of the isozyme, by means of single strand conformation polymorphism analysis of DNA fragments amplified by the polymerase chain reaction,