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Point mutations in the Drosophila sodium channel gene para associated with resistance to DDT and pyrethroid insecticides

โœ Scribed by Pittendrigh, B. ;Reenan, R. ;ffrench-Constant, R. H. ;Ganetzky, B.


Publisher
Springer
Year
1997
Tongue
English
Weight
319 KB
Volume
256
Category
Article
ISSN
0026-8925

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The voltage-sensitive sodium channel is generally regarded as the primary target site of dichloro-diphenyl-trichloro-ethane (DDT) and pyrethroid insecticides, and has been implicated in the widely reported mechanism of nerve insensitivity to these compounds. This phenomenon is expressed as knockdown