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PMN cells from chronic myeloid leukemia (CML) patients show defective chemotaxis in remission

โœ Scribed by Nishigandha R. Naik; Suresh H. Advani; Avinash N. Bhisey


Book ID
113239043
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
560 KB
Volume
13
Category
Article
ISSN
0145-2126

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Binding of chemoattractant to polymorphonuclear leukocytes (PMNL) triggers a series of events like polymerization of actin and tubulin, orientation of cells, chemotaxis, increase in fluid pinocytosis and phagocytosis, and stimulation of microbicidal pathways which includes lysosomal degranulation an