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Pleiotrophin stimulates tyrosine phosphorylation of β-adducin through inactivation of the transmembrane receptor protein tyrosine phosphatase β/ζ

✍ Scribed by Harold Pariser; Pablo Perez-Pinera; Laura Ezquerra; Gonzalo Herradon; Thomas F. Deuel


Book ID
116291018
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
294 KB
Volume
335
Category
Article
ISSN
0006-291X

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## Abstract Pleiotrophin (PTN) is a secreted growth factor involved in angiogenesis and tumor growth. We have recently shown that low concentrations of hydrogen peroxide (HP) stimulate PTN expression, through activation of the transcription factor AP‐1. In the present work, we studied the possible