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Platinum disposition after intraarterial and intravenous infusion of cisplatin for osteosarcoma

✍ Scribed by Stefan S. Bielack; Rudolf Erttmann; Guido Looft; Christine Purfürst; Günther Delling; Kurt Winkler; Günther Landbeck


Book ID
104687242
Publisher
Springer
Year
1989
Tongue
English
Weight
597 KB
Volume
24
Category
Article
ISSN
0344-5704

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✍ WILLIAM D. FIGG; MICHAELE C. CHRISTIAN; RICHARD LUSH; CHARLES J. LINK; PATRICIA 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 185 KB

Preclinical data suggest that ormaplatin (tetrachloro-(d1-trans)-1, 2-diamminocyclohexaneplatinum) has substantial activity in cisplatin-resistant tumor models and may be less nephrotoxic than cisplatin. Based on these data we initiated a phase I clinical trial in patients with refractory metastatic