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Platelet α-adrenoceptors in heroin addicts during withdrawal and after treatment with clonidine

✍ Scribed by Jesus A. Garcia-Sevilla; Luisa Ugedo; Isabel Ulibarri; Miguel Gutierrez

Book ID
115879290
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
722 KB
Volume
114
Category
Article
ISSN
0014-2999

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✍ Jesús A. García-Sevilla; Luisa Ugedo; Isabel Ulibarri; Miguel Gutierrez 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 446 KB

The density of platelet c~z-adrenoceptors, quantified by means of the binding of [3H]clonidine, and the aggregation response induced by adrenaline, was investigated in ten heroin addicts. The number of binding sites for [3H]clonidine was significantly increased during heroin abuse. Concomitantly, th