Platelet uptake of GABA and glutamate in patients with bipolar disorder
β Scribed by Simona Daniele; Eleonora Da Pozzo; Marianna Abelli; Anna Panighini; Stefano Pini; Camilla Gesi; Lisa Lari; Alessandra Cardini; Giovanni Battista Cassano; Claudia Martini
- Book ID
- 115100558
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 225 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1398-5647
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Active uptake of serotonin (5-HT) by blood platelets with bipolar primary affective disorder-bipolar type has been compared to that of their family members and healthy controls, and K~ and Vma x values were calculated for each subject. The uptake of patients' platelets, as reflected by Vmax, was fou
This study examined bipolar patients in the manic and depressed phases of bipolar disorder and controls, measuring basal radiolabelled 45Ca2+ uptake into platelets, and the effects of verapamil and flunarazine on uptake. Radiolabelled 45Ca2f uptake into platelets was measured in the manic ( N = 13)