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PLATELET-DERIVED GROWTH FACTORS AS POSSIBLE MEDIATORS OF VASCULAR PROLIFERATION IN THE SPORADIC HAEMOLYTIC URAEMIC SYNDROME

โœ Scribed by Levin, Michael; Walters, MartinD.S.; Waterfield, MichaelD.; Stroobant, Paul; Cheng, DorothyJ.; Barratt, T.Martin


Book ID
121887173
Publisher
The Lancet
Year
1986
Tongue
English
Weight
584 KB
Volume
328
Category
Article
ISSN
0140-6736

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Proliferation of smooth muscle cells from the pulmonary arteries and aortas of fetal calves is inhibited by heparin in vitro. This effect is reversible and dose dependent. Comparisons with effects of other polysaccharides indicate that only extensively sulfated polysaccharides inhibit proliferation