Platelet-Derived Growth Factor Pathway Inhibitors in Ovarian Cancer
β Scribed by Jordan Schmitt; Daniela Matei
- Book ID
- 118235051
- Publisher
- CIG Media Group, LP.
- Year
- 2008
- Tongue
- English
- Weight
- 319 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1941-4390
No coin nor oath required. For personal study only.
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Angiogenesis is a crucial event in the progression of diabetic retinopathy. Migration and proliferation of endothelial cells (EC) are important steps in angiogenesis and are caused by angiogenic factors such as basic fibroblast growth factor (bFGF). In this work, capillary EC were isolated from rabb
Platelet-derived growth factor (PDGF) is a 30 kDa protein consisting of disulfide-bonded dimers of Aand B-chains. PDGF receptors are of two types, a-and @-receptors, which are members of the protein-tyrosine kinase family of receptors. The receptors are activated by ligand-induced dimerization, wher