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PLATELET-DERIVED GROWTH FACTOR AND ITS ROLE IN ATHEROGENESIS: A BRIEF REVIEW

✍ Scribed by Marc Tennant; John K. McGeachie

Book ID
119843652
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
608 KB
Volume
61
Category
Article
ISSN
1445-1433

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Platelet-derived growth factor (PDGF) is a potent activator for cells of mesenchymal origin. PDGF stimulates chemotaxis, proliferation, and new gene expression in monocytes-macrophages and fibroblasts in vitro, cell types considered essential for tissue repair. Therefore, we analyzed the influence o