Platelet-activating factor stimulation of p125FAK and p130Cas tyrosine phosphorylation in brain
✍ Scribed by M.Carmen Calcerrada; R.Edgardo Catalán; Marı́a J Pérez-Alvarez; Begoña G Miguel; Ana M Martı́nez
- Book ID
- 114005084
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 342 KB
- Volume
- 835
- Category
- Article
- ISSN
- 0006-8993
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📜 SIMILAR VOLUMES
The experiments presented here were designed to examine the contribution of the extracellular signal-regulated mitogen-activated protein kinases (ERKs) to the tyrosine phosphorylation of the focal adhesion proteins p125 Fak , p130 Cas , and paxillin induced by G protein-coupled receptors (GPCRs) and
## Abstract Treatment of intact Swiss 3T3 cells with calyculin‐A, an inhibitor of myosin light chain (MLC) phosphatase, induces tyrosine phosphorylation of p125^Fak^ in a sharply concentration‐ and time‐dependent manner. Maximal stimulation was 4.2 ± 2.1‐fold (n = 14). The stimulatory effect of cal