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Activation of m3 Muscarinic Receptors Induces Rapid Tyrosine Phosphorylation of p125FAK, p130cas, and Paxillin in Rat Pancreatic Acini

✍ Scribed by Juan A. Rosado; Ginés M. Salido; Luis J. Garcı́a

Book ID
115568168
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
241 KB
Volume
377
Category
Article
ISSN
0003-9861

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## Abstract Treatment of intact Swiss 3T3 cells with calyculin‐A, an inhibitor of myosin light chain (MLC) phosphatase, induces tyrosine phosphorylation of p125^Fak^ in a sharply concentration‐ and time‐dependent manner. Maximal stimulation was 4.2 ± 2.1‐fold (n = 14). The stimulatory effect of cal