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Platelet-Activating Factor, PAF Acetylhydrolase, and Severe Anaphylaxis

✍ Scribed by Vadas, Peter; Gold, Milton; Perelman, Boris; Liss, Gary M.; Lack, Gideon; Blyth, Thomas; Simons, F. Estelle R.; Simons, Keith J.; Cass, Dan; Yeung, Jupiter

Book ID
121219401
Publisher
Massachusetts Medical Society
Year
2008
Tongue
English
Weight
261 KB
Volume
358
Category
Article
ISSN
0096-6762

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Platelet-activating factor (PAF) acetylhydrolase activity, LIS1 expression, and seizures
✍ Orit Shmueli; Aviv Cahana; Orly Reiner πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 108 KB πŸ‘ 2 views

Lissencephaly patients are born with severe brain malformations and suffer from recurrent seizures. LIS1, the gene mutated in isolated lissencephaly patients, is a subunit of the heterotrimeric cytosolic enzyme platelet-activating factor acetylhydrolase (PAF-AH), interacts with tubulin, and affects