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Platelet-activating factor analogs. II. Synthesis of the 1-O-(4-decyloxymethylphenyl)- and 1-O-(4-decyloxyphenylmethyl) analogs

โœ Scribed by R.C. Anderson; B.E. Reitter; C.M. Winslow

Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
472 KB
Volume
39
Category
Article
ISSN
0009-3084

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โœฆ Synopsis

1-O-(4-Decyloxymethylphenyl)-and 1-O-(4-decyloxyphenylmethyl)-2-O-acetyl-glycero-3phosphorylcholine were synthesized from 2,2-dimethyl-l,3-dioxolane-4-methanol. The utility of a 2-O-tetrahydropyranyl ether as a protecting group and its facile removal in the pre~nce of a 3-phosphorylcholine is illustrated.

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