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Plasminogen activator inhibitor-1 deficiency enhances flow-induced smooth muscle cell migration

✍ Scribed by John P Cullen; Suzanne M Nicholl; Shariq Sayeed; James V Sitzmann; S.Steve Okada; Paul A Cahill; Eileen M Redmond


Book ID
116912981
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
434 KB
Volume
114
Category
Article
ISSN
0049-3848

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Plasminogen activator inhibitor type-1 g
✍ Rohan Samarakoon; Craig E. Higgins; Stephen P. Higgins; Stacie M. Kutz; Paul J. πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 536 KB

## Abstract Transforming growth factor‐β1 (TGF‐β1) stimulates expression of plasminogen activator inhibitor type‐1 (PAI‐1), a serine protease inhibitor (__SERPIN__) important in the control of stromal barrier proteolysis and cell‐to‐matrix adhesion. Pharmacologic agents that target MEK (PD98059, U0