Propylthiouracil is a commonly used medication for hyperthyroidism. Though propylthiouracil-induced hepatotoxicity is a rarely encountered problem, death due to fulminant hepatic failure may occur. In the English literature, only 34 cases have been described with severe hepatotoxicity secondary to t
Plasmapheresis in the treatment of hyperthyroidism associated with agranulocytosis: A case report
✍ Scribed by Birol Guvenc; Cagatay Unsal; Emel Gurkan; Süleyman Dincer
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 64 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0733-2459
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✦ Synopsis
Abstract
Plasmapheresis, also known as therapeutic plasma exchange, is used in the treatment of several disorders. Temporary improvement after plasmapheresis in cases with thyrotoxicosis has been reported. A 55‐year‐old woman presented with agranulocytosis induced by propylthiouracil and clinical signs of heart failure. Three sessions of plasmapheresis were performed. We observed an improvement of thyroid hormone levels and clinical findings as well. Plasmapheresis can be an option when drug treatment of thyrotoxicosis fails. J. Clin. Apheresis 19:148–150, 2004. © 2004 Wiley‐Liss, Inc.
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