✦ LIBER ✦

Successful treatment of subacute cerebellar degeneration in ovarian carcinoma with plasmapheresis a case report

✍ Scribed by Giorgio Cocconi; Guido Ceci; Giulio Juvarra; Maria Rosaria Minopoli; Tiziano Cocchi; Franco Fiaccadori; Alfredo Lechi; Paola Boni

Publisher: John Wiley and Sons
Year: 1985
Tongue: English
Weight: 354 KB
Volume: 56
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19851101)56:9<2318::aid-cncr2820560930>3.0.co;2-9

No coin nor oath required. For personal study only.

✦ Synopsis

Subacute cerebellar degeneration is a rare complication of some neoplasms, and is generally resistant to therapy. A case of subacute cerebellar degeneration in a 50-year-old woman with a Stage I1 grade 3 serous ovarian adenocarcinoma is reported. The onset of the neurologic symptoms preceded the diagnosis of cancer and progressively worsened during and after four cycles of chemotherapy. A quick, partial improvement of the neurologic syndrome was documented after three weekly treatments with plasmapheresis. The contribution of circulating factors in inducing subacute cerebellar degeneration can be postulated. A trial using this new type of treatment should be performed in patients who have this therapeutically refractory clinical condition.

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