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Plasmalemmal dihydropyridine receptors modify the function of subplasmalemmal inositol 1,4,5-trisphosphate receptors: a hypothesis

✍ Scribed by A. Spät; T. Rohács; L. Hunyady


Book ID
113236655
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
830 KB
Volume
15
Category
Article
ISSN
0143-4160

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## Abstract At the time of fertilization, an increase in the intracellular Ca^2+^ concentration ([Ca^2+^]~i~) underlies egg activation and initiation of development in all species studied to date. The inositol 1,4,5‐trisphosphate receptor (IP~3~R1), which is mostly located in the endoplasmic reticu