PLASMA UPTAKE OF DOPAMINE AND 5-HYDROXYTRYPTAMINE AND PLASMA-CATECHOLAMINE LEVELS IN PATIENTS WITH HUNTINGTON'S CHOREA
โ Scribed by Aminoff, M.J.; Trenchard, A.; Turner, P.; Wood, W.G.; Hills, M.
- Book ID
- 121978714
- Publisher
- The Lancet
- Year
- 1974
- Tongue
- English
- Weight
- 235 KB
- Volume
- 304
- Category
- Article
- ISSN
- 0140-6736
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The effects of protriptyline and clomipramine, at concentrations of 10(-7)M to 10(-4)M, were studied in vitro on the uptake of 5-hydroxytryptamine and dopamine uptake in human platelet-rich plasma. It was found that the tertiary amine, clomipramine, was a more potent inhibitor of 5-hydroxytryptamine