## BACKGROUND. Malignant pleural mesothelioma is associated in up to 70% of cases with an elevated content of hyaluronan (HYA) in the pleural fluid. Increased levels of circulating HYA have also been described. The clinical course of the disease can be followed by computed tomography (CT), althoug
Plasma prolactin as an indicator of disease progression in advanced breast cancer
✍ Scribed by Joytsna M. Bhatavdekar; Neelam G. Shah; Damodar B. Balar; Devendra D. Patel; Anita Bhaduri; Sunil N. Trivedi; Neelkamal H. Karelia; Nandita Ghosh; Minakshi K. Shukla; Dilip D. Giri
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 435 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
Serial plasma prolactin levels were measured in 144 breast cancer patients (premenopausal [PR-MI, N = 64; postmenopausal [PO-MI, N = 80) and compared with respective controls. Patients with breast cancer were grouped into those who (1) developed distant metastasis, (2) developed local recurrence, (3) stable disease, and (4) responded to the various therapeutic modalities at the end of 2 years. The authors' analysis showed excellent correlation between serial plasma prolactin changes and the response to therapy or progression of disease in patients with advanced breast carcinoma.
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