Histopathological factors which might explain inconsistency in published data attempting to correlate oestrogen receptor content (ER) and pathological features in primary breast tumours have been investigated in 194 cases. It was found, that unequal assessment of tumour type and of histological grad
Plasma oestrogens and oestrogen receptors in breast cancer patients
โ Scribed by Mason, R C; Miller, W R; Hawkins, R A
- Book ID
- 109835678
- Publisher
- Nature Publishing Group
- Year
- 1985
- Tongue
- English
- Weight
- 465 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0007-0920
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The allele frequencies of three restriction fragment length polymorphisms at the oestrogen receptor (ESR) locus were compared between breast cancer patients and controls. Leucocyte or tumour DNA from 238 and 122 patients, respectively, and leucocyte DNA from 672 controls was analysed. Alleles having
The first studies of oestrogen receptor (ER) focused on measurements of levels in breast cancers and relationship to hormonal response, but the introduction of antibodies which can be used on fixed tissue has meant that ER can be studied in detail in normal and precancerous tissue. Cloning and seque
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