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Plasma L-[18F]6-Fluorodopa Input Function: A Simplified Method

✍ Scribed by Chan, Grace L.-Y.; Morrison, K. Scott; Holden, James E.; Ruth, Thomas J.


Book ID
109870480
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
291 KB
Volume
12
Category
Article
ISSN
0271-678X

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Kinetic modeling of the PET tracer 6-[18F]fluoro-L-dopa ([18F]Dopa), used to measure presynaptic dopamine function, requires the accurate determination of the plasma input curve. We have developed a new method that uses alumina extraction preceded by cation and anion exchange resins to determine the