Plasma clonidine concentration and pharmacologic effect
โ Scribed by Hogan, Michael J; Wallin, John D; Chu, Li-Chiang
- Book ID
- 109843134
- Publisher
- Nature Publishing Group
- Year
- 1981
- Tongue
- English
- Weight
- 290 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0009-9236
No coin nor oath required. For personal study only.
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We studied the effect of the az-adrenoceptor agonist, clonidine, and bright artificial light (>2500 lux) on the nocturnal increase in plasma melatonin in normal subjects. Clonidine (1.5 pg/ kg, intravenously) was without effect on plasma melatonin concentration. In contrast, bright light treatment a