Plasma binding of benzodiazepines in humans
โ Scribed by R. F. Johnson; S. Schenker; R. K. Roberts; P. V. Desmond; G. R. Wilkinson
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 331 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0022-3549
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Benzodiazepines can regulate neoplastic growth and immune response through specific peripheral benzodiazepine receptors. We investigated the presence of peripheral and classic central benzodiazepine receptors as well as diazepambinding inhibitor, an endogenous ligand of both types of receptors, in d
## Abstract Chlorodesmethyldiazepam (I) concentrations were followed for 72 h in the plasma of four volunteers given 2 mg of the drug orally. The drug appears to be well absorbed, reaching peak plasma levels of 20โ30 ng ml^โ1^ 1โ2 h after administration; 72 h after administration, plasma concentrat