The influence of caffeine (60 mg) was studied on the pharmacokinetic characteristics of acetaminophen (500 mg single dose) in ten healthy male human volunteers in a complete cross-over design. A high-performance liquid chromatography (HPLC) method was used to analyse serum drug concentrations. Caffe
Plasma and salivary pharmacokinetics of caffeine in man
β Scribed by R. Newton; L. J. Broughton; M. J. Lind; P. J. Morrison; H. J. Rogers; I. D. Bradbrook
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 975 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0031-6970
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## Abstract The metabolism and pharmacokinetics of intravenously administered theophylline (100 mg) have been investigated in three healthy male volunteers who consumed 6 bottles day of a cola beverage, in addition to their usual intake of methylxanthines, for 7 days prior to and during the study.