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Plasma 8-methoxypsoralen concentrations in photochemotherapy of psoriasis

✍ Scribed by I.H. STEVENSON; K.J.A. KENICER; B.E. JOHNSON; W. FRAIN-BELL


Book ID
108657525
Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
968 KB
Volume
104
Category
Article
ISSN
0007-0963

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A method based on a combination of cell culture and pharmacokinetic data is explored as a way of estimating the possible genetic risk to man from a mutagenic chemical. 8-methoxypsoralen, which is given to psoriasis patients as part of a photochemotherapy regime, is used, since it represents a 'real-