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New galenical form of 8-methoxypsoralen in photochemotherapy of psoriasis

✍ Scribed by A. Langner; H. Wolska


Publisher
Springer-Verlag
Year
1981
Tongue
English
Weight
93 KB
Volume
271
Category
Article
ISSN
0340-3696

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Serum levels of 8-methoxypsoralen in pso
✍ M. J. Herfst; E. A. M. Koot-Gronsveld; F. A. Wolff πŸ“‚ Article πŸ“… 1978 πŸ› Springer-Verlag 🌐 English βš– 291 KB

A method is described for the determination of 8-methoxypsoralen in human serum using a fluorodensitometric method. The fluorescence densitometry was carried out directly on the thin layer plate. The developing fluid consisted of chloroform/methanol. In patients with psoriasis after oral application

Determination of 8-methoxypsoralen level
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An improved fluorodensitometric assay for the determination of 8methoxypsoralen (8-MOP) in plasma is described. Because of its low limit of detection (below 1 rig/spot) this method is suitable to determine the drug in skin suction blister fluid, too. The standard deviation of the procedure is 6.4 %