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Plasma 5-Aminolevulinic Acid Concentration and Lead Exposure in Children

โœ Scribed by Pornchai Sithisarankul; Maureen Cadorette; Cecilia T. Davoli; Janet R. Serwint; James J. Chisolm Jr.; Paul T. Strickland


Book ID
115600956
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
125 KB
Volume
80
Category
Article
ISSN
0013-9351

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Aminolevulinic acid dehydratase genotype
โœ Pornchai Sithisarankul; Brian S. Schwartz; Byung-Kook Lee; Karl T. Kelsey; Paul ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 62 KB ๐Ÿ‘ 2 views

The first intermediate substrate in the heme synthetic pathway, 5-aminolevulinic acid (ALA), is neurotoxic in animal models and may be responsible for some of the adverse neurologic outcomes in lead poisoning and porphyria in adult humans. ALA is a substrate for the enzyme aminolevulinic acid dehydr