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Plant mitochondrial RNA editing: The Strasbourg chapter

✍ Scribed by Jean Michel Grienenberger


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
70 KB
Volume
61
Category
Article
ISSN
1521-6543

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✦ Synopsis


Abstract

For 8 years, it was not understood why certain genes of plant mitochondria contain CGG (arginine) codons at positions where tryptophan codons (UGG) are present in the corresponding genes of nonplant species. Identification and sequencing of a tRNA^Trp^ gene showed that it is not able to decode the CGG codon. Analysis of different discrepancies in the sequences of plant mitochondrial proteins prompted us to determine directly the corresponding RNA sequences. These experiments showed that plant mitochondrial transcripts are subject to RNA editing that changes C into U, resulting in a better phylogenetic conservation of protein sequences [Gualberto et al. (1989) Nature 341, 660–662]. Β© 2009 IUBMB IUBMB Life, 61: 1110–1113, 2009


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