✦ LIBER ✦

Pituitary-adrenal interaction and growth of the embryonic avian adrenal gland

✍ Scribed by Girouard, R. J. ;Hall, B. K.

Publisher: John Wiley and Sons
Year: 1973
Tongue: English
Weight: 690 KB
Volume: 183
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1401830306

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Possible interactions between the anterior pituitary and the adrenal gland in the embryonic chick were investigated. Hypophysectomy by partial decapitation, and treatment of embryos with dexamethasone phosphate (a potent corticosteroid) both significantly reduced the growth of the adrenal gland, indicating a dependence of the adrenal gland on the pituitary for normal growth and the potential for negative feedback between the adrenal and the pituitary.

The hyperplasia of the host adrenal gland known to follow injection of
homogenates of adrenal glands was inhibited when homogenates were injected
into embryos whose ACTH production had been inhibited by dexamethasone.
It was concluded that the response of the embryonic adrenal gland to growth
stimulating agents was mediated via the anterior pituitary.

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