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Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) and Insulin Secretion: Effects and Mechanisms

✍ Scribed by SVEN KARLSSON; KRISTIAN MOLLER; FRANK SUNDLER; BO AHRÉN

Book ID: 111392196
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 278 KB
Volume: 805
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.1996.tb17516.x

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The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is present in many regions of the adult and developing brain as are receptors for PACAP. PACAP stimulates different signalling cascades in neurons, involving cAMP, MAP kinase, and calcium. These characteristics suggest that