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Effects of pituitary adenylate cyclase activating polypeptide (PACAP) on the cardiovascular system

✍ Scribed by Yoshinobu Suzuki; Kikuo Kasai; Kazuhiro Takekoshi; Muneo Oka; Nobuyuki Banba; Toshiyuki Numao; Hiroyuki Sugimura; Masahiko Iizuka; Shin-Ichi Shimoda

Book ID: 119118166
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 566 KB
Volume: 47
Category: Article
ISSN: 0167-0115
DOI: 10.1016/0167-0115(93)90426-9

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The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is present in many regions of the adult and developing brain as are receptors for PACAP. PACAP stimulates different signalling cascades in neurons, involving cAMP, MAP kinase, and calcium. These characteristics suggest that