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Piperlongumine induces cell death through ROS-mediated CHOP activation and potentiates TRAIL-induced cell death in breast cancer cells

✍ Scribed by Jin, Hyeon-Ok; Lee, Yun-Han; Park, Jin-Ah; Lee, Ha-Na; Kim, Jin-Hee; Kim, Ji-Young; Kim, BoRa; Hong, Sung-Eun; Kim, Hyun-Ah; Kim, Eun-Kyu; Noh, Woo Chul; Kim, Jong-Il; Chang, Yoon Hwan; Hong, Seok-Il; Hong, Young-Jun; Park, In-Chul; Lee, Jin Kyung

Book ID
126803892
Publisher
Springer-Verlag
Year
2014
Tongue
English
Weight
1003 KB
Volume
140
Category
Article
ISSN
1432-1335

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We demonstrated the induction of cell death in a hepatoma cell line by IFN-gamma and its possible mechanism. Among the 2 hepatitis B virus (HBV)-associated hepatoma cell lines, SNU-354 and SNU-368, IFN-gamma induced cell death and increased caspase-3 activity in SNU-368 but not in SNU-354. IFN-gamma