𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation

✍ Scribed by Kadowaki, H; Nishitoh, H; Urano, F; Sadamitsu, C; Matsuzawa, A; Takeda, K; Masutani, H; Yodoi, J; Urano, Y; Nagano, T


Book ID
110016841
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
267 KB
Volume
12
Category
Article
ISSN
1350-9047

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Integrins mediate β-amyloid-induced cell
✍ Giuseppina Frasca; Viviana Carbonaro; Sara Merlo; Agata Copani; Maria Angela Sor 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB

## Abstract Early intracellular events responsible for cell‐cycle induction by β‐amyloid (Aβ) in neurons have not been identified yet. Extracellular signal–regulated kinases 1/2 (ERK1/2) have been identified in this pathway, and inhibition of ERK activity prevents cell‐cycle activation and reduces

Transforming growth factor β2 autocrinal
✍ Yuichi Hashimoto; Mikiro Nawa; Tomohiro Chiba; Sadakazu Aiso; Ikuo Nishimoto; Ma 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 788 KB

## Abstract Amyloid β (Aβ), the major component of the senile plaques of Alzheimer's disease, is implicated in neuronal cell death. We have found that Aβ42, a neurotoxic form of Aβ peptide, induces both neuronal and glial expression of TGFβ2. We have further demonstrated that the addition into cult