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PINK1 Overexpression Protects Against C2-ceramide-Induced CAD Cell Death Through the PI3K/AKT Pathway

✍ Scribed by Ruth Mélida Sánchez-Mora, Humberto Arboleda, Gonzalo Arboleda

Book ID: 113093546
Publisher: Humana Press Inc
Year: 2012
Tongue: English
Weight: 948 KB
Volume: 47
Category: Article
ISSN: 0895-8696
DOI: 10.1007/s12031-011-9687-z

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## Abstract Corticosterone (CORT) is well known to induce neuronal damage in various brain regions including the hippocampus, but the precise mechanism(s) of action underlying these effects has yet to be fully established. Insulin‐like growth factor‐1 (IGF‐1) is a trophic factor promoting cell surv