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Acute estradiol protects CA1 neurons from ischemia-induced apoptotic cell death via the PI3K/Akt pathway

✍ Scribed by Teresa Jover-Mengual; Takahiro Miyawaki; Adrianna Latuszek; Enrique Alborch; R. Suzanne Zukin; Anne M. Etgen


Book ID
113504819
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
808 KB
Volume
1321
Category
Article
ISSN
0006-8993

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✍ Atsumi Nitta; Wen-Hua Zheng; RΓ©mi Quirion πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 190 KB

## Abstract Corticosterone (CORT) is well known to induce neuronal damage in various brain regions including the hippocampus, but the precise mechanism(s) of action underlying these effects has yet to be fully established. Insulin‐like growth factor‐1 (IGF‐1) is a trophic factor promoting cell surv