## Abstract The SH2 domain containing inositol 5โphosphatase 2 (SHIP2) belongs to the family of the mammalian inositol polyphosphate 5โphosphatases. The two closely related isoenzymes SHIP1 (or SHIP) and SHIP2 contain a Nโterminal SH2 domain, a catalytic domain, potential PTB domainโbinding sites (
PIKfyve: the road to PtdIns 5-P and PtdIns 3,5-P2
โ Scribed by Assia Shisheva
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 261 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1065-6995
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## Abstract The biological and pathophysiological significance of class II phosphoinositide 3โkinase enzyme expression currently remains unclear. Using an in vitro scrape wound assay and timeโlapse video microscopy, we demonstrate that cell motility is increased in cultures expressing recombinant P
A bound state \(\mathrm{CO}^{+}\)of \(\mathrm{KI}\) is found, which correlates to the atomic asymptote \(\mathrm{K}\left(4 p^{2} P_{3 / 2}\right)+\) I( \(\left.5 p^{52} P_{3 / 2}\right)\) and has an internuclear distance of \(3.7356(88) \AA\) and a dissociation energy of \(893.1(50)\) \(\mathrm{cm}^