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Pigment Epithelium-Derived Factor Inhibits Lysosomal Degradation of Bcl-xL and Apoptosis in HepG2 cells

โœ Scribed by Takumi Kawaguchi; Sho-ichi Yamagishi; Minoru Itou; Koji Okuda; Shuji Sumie; Ryoko Kuromatsu; Masahiro Sakata; Mitsuhiko Abe; Eitaro Taniguchi; Hironori Koga; Masaru Harada; Takato Ueno; Michio Sata


Book ID
117971031
Publisher
American Society for Investigative Pathology
Year
2010
Tongue
English
Weight
550 KB
Volume
176
Category
Article
ISSN
0002-9440

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โœ Yi Wei Lu; Yu Dan Ren; Jing Bai; Wei Ning Chen ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 293 KB ๐Ÿ‘ 2 views

## Abstract We have recently reported that the naturally occurring spliced variant of Hepatitis B virus protein, HBSP, displayed proapoptotic activity through its BH3 domain. To investigate whether the BH3 domain in HBSP interacted with Bclโ€2 family of proteins, HBSP and Bclโ€2 family of proteins we