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PICK1 binds to calcineurin B and modulates the NFAT activity in PC12 cells

✍ Scribed by Tsutomu Iida; Hiroshi Egusa; Makio Saeki; Hirofumi Yatani; Yoshinori Kamisaki


Book ID
116297333
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
314 KB
Volume
375
Category
Article
ISSN
0006-291X

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Nuclear extract of human erythroleukemic cell line KjG2 contains a 70 kDa protein which is gradually reduced when cells are induced to express globin genes by 25 FM hemin. When globin synthesis was inhibited by cycloheximide (100 pg/ml) or Actinomycin D (1 Fg/ml), the disappearance of this protein w