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Pichia pastoris, an alternative for expression of epidermal protease inhibitors

โœ Scribed by Wichmann, N.; Christophers, E.; Wiedow, O.

Book ID
119562134
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
201 KB
Volume
16
Category
Article
ISSN
0923-1811

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## Abstract Cathepsin K is a cysteine protease of the papain family, which is predominantly expressed in osteoclasts, and is regarded as a key protease in bone remodeling. To facilitate structural studies of the protein, the wildโ€type sequence of the protease has been mutated so as to replace a pot