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Physiologically Based Pharmacokinetic (PBPK) Modeling in Children

✍ Scribed by Barrett, J S; Della Casa Alberighi, O; Läer, S; Meibohm, B


Book ID
120067403
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
299 KB
Volume
92
Category
Article
ISSN
0009-9236

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Physiologically based pharmacokinetic (P
✍ Olivier Luttringer; Frank-Peter Theil; Patrick Poulin; Anne H. Schmitt-Hoffmann; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB

The objective of this study was to use in synergy physiologically based and empirical approaches to estimate the drug-specific input parameters of PBPK models of disposition to simulate the plasma concentration-time profile of epiroprim in human. The estimated input parameters were the tissue:plasma