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Physiological vitreous changes may contribute to the pathogenesis of macular degeneration

✍ Scribed by Bettine C. P. Polak; Peter J. Ringens; Jan G. F. Worst


Book ID
117966279
Publisher
Wiley (Blackwell Publishing)
Year
2012
Tongue
English
Weight
172 KB
Volume
90
Category
Article
ISSN
1755-375X

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Epigenetic models for tumor formation assume that oncogenic transformation results from changes in the activity of otherwise normal genes. Since gene activity can be inhibited by DNA methylation, and inactivation of tumor suppressor genes is a fundamental process in oncogenesis, we investigated the