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Physiological pharmacokinetic modeling of inhaled trichloroethylene in rats

โœ Scribed by Cham E. Dallas; James M. Gallo; Raghupathy Ramanathan; Srinivasa Muralidhara; James V. Bruckner

Book ID
114087351
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
934 KB
Volume
110
Category
Article
ISSN
0041-008X

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Physiologically Based Pharmacokinetic Mo
Physiologically Based Pharmacokinetic Models for the Transport of Trichloroethylene in Adipose Tissue
โœ R.A. Albanese; H.T. Banks; M.V. Evans; L.K. Potter ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Springer ๐ŸŒ English โš– 747 KB

In this paper we present three physiologically based pharmacokinetic (PBPK) models for the systemic transport of trichloroethylene (TCE), with a focus on the adipose, or fat tissue. TCE is a widespread environmental contaminant, and has been shown to produce toxic effects in both animals and humans.