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Physiologically based pharmacokinetic modeling of inhaled 2-butoxyethanol in man

✍ Scribed by Johanson, Gunnar

Book ID
122048413
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
537 KB
Volume
34
Category
Article
ISSN
0378-4274

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Physiologically based pharmacokinetic mo
Physiologically based pharmacokinetic modeling of cyclotrimethylenetrinitramine in male rats
✍ Kannan Krishnan; Lee C.B. Crouse; Matthew A. Bazar; Michael A. Major; Gunda Redd πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 369 KB

## Abstract A physiologically based pharmacokinetic (PBPK) model for simulating the kinetics of cyclotrimethylene trinitramine (RDX) in male rats was developed. The model consisted of five compartments interconnected by systemic circulation. The tissue uptake of RDX was described as a perfusion‐lim