𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Physiological functions of imprinted genes

✍ Scribed by Benjamin Tycko; Ian M. Morison

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
226 KB
Volume
192
Category
Article
ISSN
0021-9541

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Genomic imprinting in gametogenesis marks a subset of mammalian genes for parent‐of‐origin‐dependent monoallelic expression in the offspring. Embryological and classical genetic experiments in mice that uncovered the existence of genomic imprinting nearly two decades ago produced abnormalities of growth or behavior, without severe developmental malformations. Since then, the identification and manipulation of individual imprinted genes has continued to suggest that the diverse products of these genes are largely devoted to controlling pre‐ and post‐natal growth, as well as brain function and behavior. Here, we review this evidence, and link our discussion to a website (http://www.otago.ac.nz/IGC) containing a comprehensive database of imprinted genes. Ultimately, these data will answer the long‐debated question of whether there is a coherent biological rationale for imprinting. © 2002 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

The role of imprinted genes in fetal gro
The role of imprinted genes in fetal growth abnormalities
✍ Jorge A. Piedrahita 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 696 KB

## Abstract Epigenetics, and in particular imprinted genes, have a critical role in the development and function of the placenta, which in turn has a central role in the regulation of fetal growth and development. A unique characteristic of imprinted genes is their expression from only one allele,

Physiological functions of FMRFamide-lik
Physiological functions of FMRFamide-like peptides (FLPs) in crustaceans
✍ A. Joffre Mercier; Rainer Friedrich; Maria Boldt 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 137 KB

## Abstract Neuropeptides play important roles in chemical signalling in the central and peripheral nervous systems. One of the largest families of neuropeptides is that of the FMRFamide‐like peptides (FLPs). This paper reviews what is known about the physiological functions of FLPs in crustaceans,

On the Natural Imprint Function of a Gra
On the Natural Imprint Function of a Graph
✍ Boštjan Brešar 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 130 KB

In this paper, some characterizations of median and quasi-median graphs are extended to general isometric subgraphs of Cartesian products using the concept of an imprint function as introduced by Tardif. This extends the well known concepts of medians in median graphs as well as imprints in quasi-me