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Physiological consequences of defects in ERCC1–XPF DNA repair endonuclease

✍ Scribed by Siobhán Q. Gregg; Andria Rasile Robinson; Laura J. Niedernhofer

Book ID
113568327
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
714 KB
Volume
10
Category
Article
ISSN
1568-7864

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## Abstract Over 80% of patients with advanced metastatic testis tumors can be cured using cisplatin‐based combination chemotherapy. This is unusual as metastatic cancer in adults is usually incurable. Cell lines derived from testis tumors retain sensitivity to cisplatin __in vitro__. We previously