Multiple roles of ERCC1-XPF in mammalian interstrand crosslink repair

Reduced levels of XPA, ERCC1 and XPF DNA

Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines

✍ Carey Welsh; Roger Day; Claire McGurk; John R.W. Masters; Richard D. Wood; Beate 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 474 KB 👁 1 views

## Abstract Over 80% of patients with advanced metastatic testis tumors can be cured using cisplatin‐based combination chemotherapy. This is unusual as metastatic cancer in adults is usually incurable. Cell lines derived from testis tumors retain sensitivity to cisplatin __in vitro__. We previously