Physiological and genetical studies on a mutant of Salmonella typhimurium which is temperature-sensitive for DNA synthesis

Studies on a chinese hamster line that i

Studies on a chinese hamster line that is temperature sensitive for the commitment to DNA synthesis

✍ B. J. Smith; N. M. Wigglesworth 📂 Article 📅 1974 🏛 John Wiley and Sons 🌐 English ⚖ 470 KB

## Abstract The Chinese hamster cell line K12 is temperature sensitive for the initiation of DNA synthesis and for the programming of rounding up to enter mitosis. Viability is lost expontentially after twelve hours at the non‐permissive temperature. This temperature sensitivity is reversed followi